lymphokine - meaning and definition. What is lymphokine
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What (who) is lymphokine - definition

CYTOKINE PRODUCED BY LYMPHOCYTES
Lymphokines

lymphokine         
['l?mf?(?)k??n]
¦ noun Physiology a substance of a type produced by lymphocytes and having an effect on other cells of the immune system.
Origin
1960s: from lympho- + Gk kinein 'to move'.
Lymphokine         
Lymphokines are a subset of cytokines that are produced by a type of immune cell known as a lymphocyte. They are protein mediators typically produced by T cells to direct the immune system response by signaling between its cells.
Lymphokine-activated killer cell         
In cell biology, a lymphokine-activated killer cell (also known as a LAK cell) is a white blood cell that has been stimulated to kill tumor cells. If lymphocytes are cultured in the presence of Interleukin 2, it results in the development of effector cells which are cytotoxic to tumor cells.

Wikipedia

Lymphokine

Lymphokines are a subset of cytokines that are produced by a type of immune cell known as a lymphocyte. They are protein mediators typically produced by T cells to direct the immune system response by signaling between its cells. Lymphokines have many roles, including the attraction of other immune cells, including macrophages and other lymphocytes, to an infected site and their subsequent activation to prepare them to mount an immune response. Circulating lymphocytes can detect a very small concentration of lymphokine and then move up the concentration gradient towards where the immune response is required. Lymphokines aid B cells to produce antibodies.

Important lymphokines secreted by the T helper cell include:

  • Interleukin 2
  • Interleukin 3
  • Interleukin 4
  • Interleukin 5
  • Interleukin 6
  • Granulocyte-macrophage colony-stimulating factor
  • Interferon-gamma